Tamper-resistant Formulation

Novel Drug Delivery Systems

We are working on the development of new platform technologies for drug delivery. These drug delivery technologies are designed to significantly improve the medical use of well-established compounds.

The improvement may be based on innovative application forms which could enhance the safety and tolerability or the compliance for the patients under treatment. In other cases, the innovative drug delivery form may allow for treatment regimen and therapeutic applications other than already indicated for the respective well established compound in its current market form.

Protecting intended drug action

Grünenthal’s tamper-resistant formulation technology (TRF) INTAC® is an approach which can significantly raise the hurdle for abuse by routes of administration which require the product to be crushed first (chewing, snorting, injecting). Grünenthal’s proprietary INTAC® approach is featured in FDA-approved products and Grünenthal considers its INTAC® to be the leading technology for abuse-deterrent and tamper-resistant opioid products.

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